RUXIENCE (rituximab for injection) infusions should be administered in a setting where fullresuscitation facilities (see SERIOUS WARNINGS AND PRECAUTIONS) are immediatelyavailable, and under the close supervision of someone experienced and capable of dealing withsevere infusion- related reactions. RUXIENCE should be administered as an IV infusion througha dedicated line. Do not administer as an intravenous push or bolus (See Administration).